Lindygirl asks…In a recent facebook post from futurederm I read this : “Believe it or not, we now know you should always use niacinamide with resveratrol. Niacinamide has many benefits, but has been shown to increase sirtuin production, which may accelerate aging. On the other hand, resveratrol has been shown to decrease sirtuin production. So [...]
Lindygirl asks…In a recent facebook post from futurederm I read this : “Believe it or not, we now know you should always use niacinamide with resveratrol. Niacinamide has many benefits, but has been shown to increase sirtuin production, which may accelerate aging. On the other hand, resveratrol has been shown to decrease sirtuin production. So get the benefits of niacinamide without the sirtuins by using it together with resveratrol.” Olay also makes Regenerist Daily Regenerating Serum, Fragrance Free. That product contains niacinamide as well, but no resveratrol. So is using it for daytime a bad idea?
The Beauty Brains respond:
Hey Lindy, could you ask an EASY question once in a while?
As regular readers of the Beauty Brains know, we’re big fans of the work that FutureDerm does. We are scratching our heads, however, over the above Facebook quote. Since there’s no reference given, we’re not clear on the evidence that lead FutureDerm team to the conclusion that niacinamide increases sirtuin production and therefore must be balanced out with resveratol to decrease sirituin production.
Niacinamide and sirtuins
The best review of this subject that we’ve seen so far was done by Marta at Truth in Aging. She reviewed several studies and found a lot of conflicting data: some studies show niacinimide increases sirtuin production while others shows it decreases it. She concludes that “the research is very nascent and the interaction of SIR2 and nicotinamide is barely understood.” That seems a prudent conclusion based on what we’ve seen.
It might sound like a corporate cop out but without clear scientific consensus on an opposing point of view, we’d put our faith in the research done by P&G which shows the benefits of using niacinamide alone. If there was clear evidence showing that niacinamide worked better with resveratrol, then it’s likely that the scientists at P&G would have already incorporated the combination into a new Olay product.
If anyone over at FutureDerm has any additional perspective, we’d love to continue the discussion in the comments section!
Image credit: http://www.iuvalladolid.org/
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